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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function.
Blazev R, Carl CS, Ng YK, Molendijk J, Voldstedlund CT, Zhao Y, Xiao D, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Blazev R, et al. Among authors: chung jd. Cell Metab. 2022 Oct 4;34(10):1561-1577.e9. doi: 10.1016/j.cmet.2022.07.003. Epub 2022 Jul 25. Cell Metab. 2022. PMID: 35882232 Free article.
Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.
Ovens AJ, Gee YS, Ling NXY, Yu D, Hardee JP, Chung JD, Ngoei KRW, Waters NJ, Hoffman NJ, Scott JW, Loh K, Spengler K, Heller R, Parker MW, Lynch GS, Huang F, Galic S, Kemp BE, Baell JB, Oakhill JS, Langendorf CG. Ovens AJ, et al. Among authors: chung jd. Biochem J. 2022 Jun 17;479(11):1181-1204. doi: 10.1042/BCJ20220067. Biochem J. 2022. PMID: 35552369 Free PMC article.
Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencing.
Tian L, Jabbari JS, Thijssen R, Gouil Q, Amarasinghe SL, Voogd O, Kariyawasam H, Du MRM, Schuster J, Wang C, Su S, Dong X, Law CW, Lucattini A, Prawer YDJ, Collar-Fernández C, Chung JD, Naim T, Chan A, Ly CH, Lynch GS, Ryall JG, Anttila CJA, Peng H, Anderson MA, Flensburg C, Majewski I, Roberts AW, Huang DCS, Clark MB, Ritchie ME. Tian L, et al. Among authors: chung jd. Genome Biol. 2021 Nov 11;22(1):310. doi: 10.1186/s13059-021-02525-6. Genome Biol. 2021. PMID: 34763716 Free PMC article.
Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.
Hardee JP, Martins KJB, Miotto PM, Ryall JG, Gehrig SM, Reljic B, Naim T, Chung JD, Trieu J, Swiderski K, Philp AM, Philp A, Watt MJ, Stroud DA, Koopman R, Steinberg GR, Lynch GS. Hardee JP, et al. Among authors: chung jd. Mol Metab. 2021 Mar;45:101157. doi: 10.1016/j.molmet.2020.101157. Epub 2020 Dec 24. Mol Metab. 2021. PMID: 33359740 Free PMC article.